Monday, September 22, 2014

Walk in for flu shot!

Our flu clinics are Mondays, Tuesdays, and Thursdays from 9-12 and from 4-5pm. No appointment necessary!

Live Long and Prosper Newsletter September 2014

This newsletter was compiled from the latest research on health and longevity, by David Donohue, MD, FACP.

Nutrition
1.   Therapeutic applications of herbal medicines for cancer patients.
   Well most herbal medicines strike out when subjected to the jaundiced rigour of Evidence-Based Medicine. But there are a few stand-outs. In particular, if I ever get lung cancer or perhaps others, I will start furiously googling "Pan-Asian medicine plus vitamins". One legit appearing study showed impressive results.
August 29, 2013

2.   Dark Chocolate: An Obesity Paradox or a Culprit for Weight Gain?
   Dark chocolate has lots of promising antioxidant phytochemicals that chocolate-loving researchers love to tout and chocolate-loving NIH staffers love to fund. Fortunately, some compelling clinical data point to slight benefits on blood pressure, blood sugar, and weight. I am a fair trade 80-85% cacao junkie myself.
September 5, 2013
Exercise
1.   Low-risk lifestyle, coronary calcium, cardiovascular events, and mortality: results from MESA.
   The more of these you did the lower your death rate: * don't smoke, * maintain a healthy weight, * healthy diet, * regular exercise. What is newish here is that they also found the coronary calcium score correlated with death as well. This is a test you can choose to pay for, as a measure of the plaque in the arteries around the heart. Mounting evidence suggests it can be predictive of your risk for heart disease and death. Of course, a simpler test is to ask yourself how well you are doing with respect to the 4 behaviors above.
September 8, 2013

2.   Usefulness of step counts to predict mortality in Japanese patients with heart failure.
   If you are Japanese and have congestive heart failure (CHF) then walk more than 4,889 steps per day or die!! Well no. Actually you face 2.28 times the risk of death if you are in the group who takes that many steps or less. We can postulate that exercise might reduce death in CHF patients, and it might benefit the rest of us.
September 15, 2013
Lifestyle
1.   Physical activity and other lifestyle factors in relation to the prevalence of colorectal adenoma: a colonoscopy-based study in asymptomatic Koreans
   People who exercise more have half the risk of colon adenomas (nasty pre-cancerous polyps).
August 31, 2013

2.   Depressive symptoms are a risk factor for all-cause mortality: results from a prospective population-based study among 3,080 cancer survivors from the PROFILES registry
   Cancer survivors who get depressed have double the rate of mortality compared with non-depressed cancer survivors.
August 31, 2013
Prevention
1.   Lifestyle and cancer prevention in women: knowledge, perceptions, and compliance with recommended guidelines.
   Study of American women - "Only 9.9% of women who reported eating a healthy diet met minimum fruit and vegetable recommendations; 39.7% of women who reported regular physical activity met the minimum recommendation."
September 27, 2013

2.   High concentrations of a urinary biomarker of polyphenol intake are associated with decreased mortality in older adults.
   People with higher levels of polyphenol in their urine had 30% lower death rate. So add some polyphenols to your urine! You could grind them up and just add to the toilet for lots of healthy toilet goodness. Well assuming there might be an ounce of causation in this relationship, maybe your best strategy is to eat some polyphenols so they end up in your urine. "From whence" you query? Berries, artichokes, coffee, flax meal, dark chocolate, tea, apples.
November 5, 2013
Safety
1.   Touch as an Interpersonal Emotion Regulation Process in Couples' Daily Lives: The Mediating Role of Psychological Intimacy.
   Touching one's boyfriend/girlfriend correlated with better well-being 6 months later. Let that be a lesson to us all.
August 22, 2013

2.   '…I've Found Once the Weight Had Gone Off, I've Had a Few Twinges, But Nothing Like Before'. Exploring Weight and Self-Management of Knee Pain.
   Knee pain very much improves with weight loss.
August 22, 2013

3.   When is acute persistent cough in school-age children and adults whooping cough?
   Do you have an active persistent cough for 2 weeks? According to this New Zealand study, there is a 10% chance you have whooping cough.
August 28, 2013
Personalized Health


   No stories found.
Medication
1.   Heart rate at rest, exercise capacity, and mortality risk in veterans.
   We are familiar with elevated blood pressure being a risk factor for heart disease and stroke and death. But what about the heart rate (number of beats per minute)? It turns out this too is a predictor of cardiovascular disease when elevated. For each increase of resting heart rate of 10 beats per minute, the investigators observed an 11% increase in mortality.
January 8, 2014

2.   Relationship between obesity and obesity-related morbidities weakens with aging.
   Older people have less health benefits from having a lower BMI, than do younger people.
February 5, 2014

Friday, September 5, 2014

Flu Shots Are In!

Our regular and high dose flu shots have now arrived.  Our flu clinics are Mondays, Tuesdays, and Thursdays from 9-12 and from 4-5pm. No appointment necessary during these times. Please stop by!

Friday, August 22, 2014

High Dose Flu Shots Available for 65+

Our high dose flu shots have arrived. This vaccine is for patients over the age of 65, and research has shown it to be more effective in that population than the standard flu shot. 

Please ask us at your office visit if you would like to receive this vaccine. 

Our regular flu vaccines should arrive around September 10th. We will be starting our walk-in flu clinics around September 15th. Stay healthy everyone!

Live Long and Prosper Newsletter August 2014

This newsletter was compiled from the latest research on health and longevity, by David Donohue, MD, FACP. 

Nutrition
1.   Is there a reverse J-shaped association between 25-hydroxyvitamin D and all-cause mortality? Results from the U.S. nationally representative NHANES.
   what is the optimal level of vitamin D in your blood? It turns out that people with a vitamin D level of about 81 live the longest. Mortality rate increases as your vitamin D level gets above 100 or less than 40. About 85% of people with body mass index over 30 have a low vitamin D level (less than 30). Does taking vitamin D supplements make you live longer? Not as clear.
October 2, 2013

2.   Obesity and early mortality in the United States.
   "CONCLUSIONS: For healthy nonsmokers young- and middle-aged adults who constitute about one-third of American adults, being obese is likely to hasten mortality by 9.44 years"
October 2, 2013

3.   Lifestyle factors and mortality risk in individuals with diabetes mellitus: are the associations different from those in individuals without diabetes?
   People who have diabetes have a 62% higher mortality rate. If you are getting diabetes, it is best to aggressively change your lifestyle and not get it. "Intake of fruit, legumes, nuts, seeds, pasta, poultry and vegetable oil was related to a lower mortality risk, and intake of butter and margarine was related to an increased mortality risk"
October 18, 2013



Exercise
1.   Association between various sedentary behaviours and all-cause, cardiovascular disease and cancer mortality: the Multiethnic Cohort Study.
   Sitting at work for more than 10 hours per day had a harmful effect on women, increasing their mortality rate by 19% relative to those who sat less than 5 hours. Sitting watching over 5 hours per day of TV was associated with 19% higher rate of cardiac death in men and 32% higher in women, relative to abstainers.
September 27, 2013

2.   Examining the Behavioral Processes through which Lifestyle Interventions Promote Weight Loss: Results from the PREMIER Trial.
   Not many things reliably help people lose weight. This study (like many others) found that adherence to a weight loss program and self-monitoring of weight both make a big difference. If you want to lose weight, probably best to eagerly participate in a program, and weigh yourself every day.
October 15, 2013

3.   Association of walking speed in late midlife with mortality: results from the Whitehall II cohort study.
   Researchers have been studying how walking speed is a measure of longevity, among people above say 50. This study confirmed this (89% higher mortality for those in the slower 1/3 of people).
October 18, 2013

Lifestyle
1.   The metabolic syndrome.
   Many people have not heard of "The Metabolic Syndrome". It has been all the rage in recent years in primary care. It goes by a number of different names: insulin resistance, glucose intolerance, pre-diabetes. It is thought to be both a risk factor for heart disease and a warning sign that you are about to get diabetes. How can you tell if you have it? Supposedly you have it if you have 3 or more of the following: * waist circumference greater than 40 inches in men or 35 in women, * serum triglycerides > 150, * HDL ("good") cholesterol l< 40 in men or < 50 in women, * blood pressure > 130/85, * fasting blood sugar > 100
August 25, 2013

2.   Better Diet Quality and Decreased Mortality Among Myocardial Infarction Survivors.
   After having a heart attack, those who ate a Mediterranean-style diet lived a little longer.
September 5, 2013

3.   The contribution of diet and lifestyle to socioeconomic inequalities in cardiovascular morbidity and mortality.
   It has long been known that people of more privileged socioeconomic background live longer on average. For example, the more years of school you have had and the more stable your employment, the longer you live. This study investigated why. They found that most (70%) of the benefit of education on preventing heart disease is because people with more education tend to have better diets and exercise habits. So education causes better eating and exercise which causes less heart disease which causes less death. That's most of the story anyway.
September 5, 2013

Prevention
1.   The “New Deadly Quartet” for Cardiovascular Disease in the 21st Century: Obesity, Metabolic Syndrome, Inflammation and Climate Change: How Does Statin Therapy Fit into this Equation?
   The authors cite evidence that particulates in the atmosphere are driving a significant amount of cardiovascular disease.
December 16, 2013

2.   Recent progress on nutraceutical research in prostate cancer
   Those who drank soymilk daily had 70% lower rate of prostate cancer than abstainers. men with prostate cancer who ate more fruits and veggies reduced their risk of progression by 59% relative to those who are the least. Green tea reduced the rate of widespread prostate cancer. In short, eating a plant-based diet and avoiding the usual suspects (meat, dairy, and eggs) is our best medicine against prostate cancer. Far tastier than PSA tests and digital rectal exams (yuck).
December 27, 2013

Safety
1.   Choice of motorcycle helmet makes a difference: a prospective observational study.
   In emergency room circles, they call them donorcycles, because that's where organ donations come from. For every mile ridden on a motorcycle, the rider has 35 times the risk of dying relative to riding in a car. But if you in that demographic of safety-conscious motorcycle riders, hear this: Riders who wear Full Face Helmets enjoy about 1/5 the risk of having a facial fracture.
September 5, 2013

2.   A prospective study of carpal tunnel syndrome: workplace and individual risk factors.
   Carpal tunnel syndrome (CTS) occurs most commonly with forceful hand exertion. Obesity triples your risk of CTS.
September 11, 2013

3.   Randomised clinical trial: sodium alginate oral suspension is non-inferior to omeprazole in the treatment of patients with non-erosive gastroesophageal disease.
   Sodium alginate oral suspension was as affective as omeprazole (Prilosec), for regular-old espohageal reflux (GERD), without ulcers or other erosions. Omeprazole and other proton-pump inhibitors (PPIs) are know to increase risk of some infections and of bone thinning. 
September 14, 2013

Wednesday, August 13, 2014

Our Phone Restored

The problems with our phone system have been resolved.  It is now operating properly.

Monday, August 11, 2014

Live Long & Prosper Newsletter August 2014

This newsletter was compiled from the latest research on health and longevity, by David Donohue, MD, FACP.

Nutrition
1.   Fruit and vegetable consumption and all-cause mortality: a dose-response analysis.
   Study of Swedes and their fruit & vegetable (FV) intake: There was a dose-response effect, meaning the more FV eaten per day, the lower the death rate (up to a point). "Those who never consumed FV lived 3 y shorter and had a 53% higher mortality rate than did those who consumed 5 servings FV/d".
September 25, 2013

2.   A comparative study of phytochemical composition of genetically and non-genetically modified soybean (Glycine max L.) and evaluation of antitumor activity.
   Consumption of soy products is associated with lower rates of colon cancer, and this study found that non-GMO soybeans had higher concentrations of the putative anticancer compounds that they tested.
September 27, 2013

Exercise
1.   The effect of selected lifestyle factors and diet on mortality of men with documented physical fitness in the city of Łódź
   Some interesting findings in men from Lodz, Poland: "The probability of death was more than fourfold higher in the case of individuals who eat "beef or pork meat", as compared to those who consumed these products rarely or never. On the other hand, the subjects who declared regular consumption of yellow cheese had nearly fourfold lower death probability. Current smoking was found to be a significant negative risk factor while moderate consumption of beer a protective one. The level of physical fitness ... did not significantly influence mortality."
September 22, 2013

2.   Infant Feeding in America: Enough to Break a Mother's Heart?
   Mothers to be, another reason to plan to breastfeed! "A growing body of literature indicates that mothers who prematurely discontinue lactation face increased risk of visceral adiposity, hypertension, hyperlipidemia, diabetes, and subclinical cardiovascular disease, as well as cardiovascular morbidity and mortality. Breastfeeding is not always easy, but neither is dieting, exercise, smoking cessation, or treating hypertension."
October 12, 2013

Lifestyle
1.   Mortality in middle-aged men with obstructive sleep apnea in Finland
   Sleep apnea (OSA) kills. At least it kills middle aged Finnish men. "The overall mortality in the moderate to severe OSA group was 26.4 %, while in the normal group it was 9.7 %". If you are overweight and snore you most likely have sleep apnea, and should get a sleep study.
August 31, 2013

2.   Obesity and Low Back Pain: Is There a Weight of Evidence to Support a Positive Relationship?
   Obesity and back pain are correlated. For each pound you lose, your risk or severity of back pain goes down by 1% (roughly)!
August 31, 2013

Prevention
1.   Diet and vitamin D as risk factors for lung impairment and COPD.
   Chronic lung disease. Add it to the list of things that seem to be helped by eating a diet rich in plant-based foods like fruits. Also, "Higher intakes of vitamin D have been associated with better lung function and a lower prevalence of COPD".
November 13, 2013

2.   Prevention of Colorectal Cancer: The Future Is Now
   Wow interesting paper. There is more you can do to prevent colon cancer than I knew about. For example aspirin, NSAID drugs, and the diabetic drug metformin significantly reduce your risk of colon cancer, like 30-50%. The evidence is strong that red and processed meats increase your risk. A sedentary lifestyle is a huge risk factor. Get physically active and reduce your colon cancer by as much as 46%. Let's not forget the important role of colon screening. If you were going to pick 1 cancer to screen for, this would be the one. Many people are unaware that in addition to the standard colonoscopy, stool card testing is an alternative approved screening method.
December 9, 2013


Safety
1.   The effectiveness of helmets in bicycle collisions with motor vehicles: a case-control study.
   Cyclists who got in accidents with a car were 74% less likely to have a head injury if they were wearing a bike helmet.
August 29, 2013

2.   Occupational safety and health enforcement tools for preventing occupational diseases and injuries.
   Review of the 23 studies: "Inspections decrease injuries in the long term but not in the short term.... First inspections, follow-up inspections, complaint and accident inspections resulted in higher compliance rates... There is an urgent need for better designed evaluations" Maybe DuPont could publish a study on the effectiveness of its safety culture and its inspections to prevent injury.
September 4, 2013

Device
1.   Note: High frequency vibration rejection using a linear shaft actuator-based image stabilizing device via vestibulo-ocular reflex adaptation control method.
   Say that 3 times fast.
September 8, 2013

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