Monday, October 13, 2014

Come Run a Charity 5K!

Progressive Health of Delaware is proud to be a sponsor for the HOPE 5K in Arden, DE on Saturday, October 25th at 9.00am.  Come run with Dr. Donohue, Dr. Zarek, and their kids as they support this worthy cause.  See more information about Premiere Charities at 

Temporarily Out of Flu Shots

We are currently out of the high dose flu vaccines for our patients 65 and older.  We expect them to be back in stock next week.  We will update our website when they have arrived.  We do have our regular flu shots available for our patients under 65.  See walk-in schedule on previous post.  Stay well!

Monday, September 22, 2014

Walk in for flu shot!

Our flu clinics are Mondays, Tuesdays, and Thursdays from 9-12 and from 4-5pm. No appointment necessary!

Live Long and Prosper Newsletter September 2014

This newsletter was compiled from the latest research on health and longevity, by David Donohue, MD, FACP.

1.   Therapeutic applications of herbal medicines for cancer patients.
   Well most herbal medicines strike out when subjected to the jaundiced rigour of Evidence-Based Medicine. But there are a few stand-outs. In particular, if I ever get lung cancer or perhaps others, I will start furiously googling "Pan-Asian medicine plus vitamins". One legit appearing study showed impressive results.
August 29, 2013

2.   Dark Chocolate: An Obesity Paradox or a Culprit for Weight Gain?
   Dark chocolate has lots of promising antioxidant phytochemicals that chocolate-loving researchers love to tout and chocolate-loving NIH staffers love to fund. Fortunately, some compelling clinical data point to slight benefits on blood pressure, blood sugar, and weight. I am a fair trade 80-85% cacao junkie myself.
September 5, 2013
1.   Low-risk lifestyle, coronary calcium, cardiovascular events, and mortality: results from MESA.
   The more of these you did the lower your death rate: * don't smoke, * maintain a healthy weight, * healthy diet, * regular exercise. What is newish here is that they also found the coronary calcium score correlated with death as well. This is a test you can choose to pay for, as a measure of the plaque in the arteries around the heart. Mounting evidence suggests it can be predictive of your risk for heart disease and death. Of course, a simpler test is to ask yourself how well you are doing with respect to the 4 behaviors above.
September 8, 2013

2.   Usefulness of step counts to predict mortality in Japanese patients with heart failure.
   If you are Japanese and have congestive heart failure (CHF) then walk more than 4,889 steps per day or die!! Well no. Actually you face 2.28 times the risk of death if you are in the group who takes that many steps or less. We can postulate that exercise might reduce death in CHF patients, and it might benefit the rest of us.
September 15, 2013
1.   Physical activity and other lifestyle factors in relation to the prevalence of colorectal adenoma: a colonoscopy-based study in asymptomatic Koreans
   People who exercise more have half the risk of colon adenomas (nasty pre-cancerous polyps).
August 31, 2013

2.   Depressive symptoms are a risk factor for all-cause mortality: results from a prospective population-based study among 3,080 cancer survivors from the PROFILES registry
   Cancer survivors who get depressed have double the rate of mortality compared with non-depressed cancer survivors.
August 31, 2013
1.   Lifestyle and cancer prevention in women: knowledge, perceptions, and compliance with recommended guidelines.
   Study of American women - "Only 9.9% of women who reported eating a healthy diet met minimum fruit and vegetable recommendations; 39.7% of women who reported regular physical activity met the minimum recommendation."
September 27, 2013

2.   High concentrations of a urinary biomarker of polyphenol intake are associated with decreased mortality in older adults.
   People with higher levels of polyphenol in their urine had 30% lower death rate. So add some polyphenols to your urine! You could grind them up and just add to the toilet for lots of healthy toilet goodness. Well assuming there might be an ounce of causation in this relationship, maybe your best strategy is to eat some polyphenols so they end up in your urine. "From whence" you query? Berries, artichokes, coffee, flax meal, dark chocolate, tea, apples.
November 5, 2013
1.   Touch as an Interpersonal Emotion Regulation Process in Couples' Daily Lives: The Mediating Role of Psychological Intimacy.
   Touching one's boyfriend/girlfriend correlated with better well-being 6 months later. Let that be a lesson to us all.
August 22, 2013

2.   '…I've Found Once the Weight Had Gone Off, I've Had a Few Twinges, But Nothing Like Before'. Exploring Weight and Self-Management of Knee Pain.
   Knee pain very much improves with weight loss.
August 22, 2013

3.   When is acute persistent cough in school-age children and adults whooping cough?
   Do you have an active persistent cough for 2 weeks? According to this New Zealand study, there is a 10% chance you have whooping cough.
August 28, 2013
Personalized Health

   No stories found.
1.   Heart rate at rest, exercise capacity, and mortality risk in veterans.
   We are familiar with elevated blood pressure being a risk factor for heart disease and stroke and death. But what about the heart rate (number of beats per minute)? It turns out this too is a predictor of cardiovascular disease when elevated. For each increase of resting heart rate of 10 beats per minute, the investigators observed an 11% increase in mortality.
January 8, 2014

2.   Relationship between obesity and obesity-related morbidities weakens with aging.
   Older people have less health benefits from having a lower BMI, than do younger people.
February 5, 2014

Friday, September 5, 2014

Flu Shots Are In!

Our regular and high dose flu shots have now arrived.  Our flu clinics are Mondays, Tuesdays, and Thursdays from 9-12 and from 4-5pm. No appointment necessary during these times. Please stop by!

Friday, August 22, 2014

High Dose Flu Shots Available for 65+

Our high dose flu shots have arrived. This vaccine is for patients over the age of 65, and research has shown it to be more effective in that population than the standard flu shot. 

Please ask us at your office visit if you would like to receive this vaccine. 

Our regular flu vaccines should arrive around September 10th. We will be starting our walk-in flu clinics around September 15th. Stay healthy everyone!

Live Long and Prosper Newsletter August 2014

This newsletter was compiled from the latest research on health and longevity, by David Donohue, MD, FACP. 

1.   Is there a reverse J-shaped association between 25-hydroxyvitamin D and all-cause mortality? Results from the U.S. nationally representative NHANES.
   what is the optimal level of vitamin D in your blood? It turns out that people with a vitamin D level of about 81 live the longest. Mortality rate increases as your vitamin D level gets above 100 or less than 40. About 85% of people with body mass index over 30 have a low vitamin D level (less than 30). Does taking vitamin D supplements make you live longer? Not as clear.
October 2, 2013

2.   Obesity and early mortality in the United States.
   "CONCLUSIONS: For healthy nonsmokers young- and middle-aged adults who constitute about one-third of American adults, being obese is likely to hasten mortality by 9.44 years"
October 2, 2013

3.   Lifestyle factors and mortality risk in individuals with diabetes mellitus: are the associations different from those in individuals without diabetes?
   People who have diabetes have a 62% higher mortality rate. If you are getting diabetes, it is best to aggressively change your lifestyle and not get it. "Intake of fruit, legumes, nuts, seeds, pasta, poultry and vegetable oil was related to a lower mortality risk, and intake of butter and margarine was related to an increased mortality risk"
October 18, 2013

1.   Association between various sedentary behaviours and all-cause, cardiovascular disease and cancer mortality: the Multiethnic Cohort Study.
   Sitting at work for more than 10 hours per day had a harmful effect on women, increasing their mortality rate by 19% relative to those who sat less than 5 hours. Sitting watching over 5 hours per day of TV was associated with 19% higher rate of cardiac death in men and 32% higher in women, relative to abstainers.
September 27, 2013

2.   Examining the Behavioral Processes through which Lifestyle Interventions Promote Weight Loss: Results from the PREMIER Trial.
   Not many things reliably help people lose weight. This study (like many others) found that adherence to a weight loss program and self-monitoring of weight both make a big difference. If you want to lose weight, probably best to eagerly participate in a program, and weigh yourself every day.
October 15, 2013

3.   Association of walking speed in late midlife with mortality: results from the Whitehall II cohort study.
   Researchers have been studying how walking speed is a measure of longevity, among people above say 50. This study confirmed this (89% higher mortality for those in the slower 1/3 of people).
October 18, 2013

1.   The metabolic syndrome.
   Many people have not heard of "The Metabolic Syndrome". It has been all the rage in recent years in primary care. It goes by a number of different names: insulin resistance, glucose intolerance, pre-diabetes. It is thought to be both a risk factor for heart disease and a warning sign that you are about to get diabetes. How can you tell if you have it? Supposedly you have it if you have 3 or more of the following: * waist circumference greater than 40 inches in men or 35 in women, * serum triglycerides > 150, * HDL ("good") cholesterol l< 40 in men or < 50 in women, * blood pressure > 130/85, * fasting blood sugar > 100
August 25, 2013

2.   Better Diet Quality and Decreased Mortality Among Myocardial Infarction Survivors.
   After having a heart attack, those who ate a Mediterranean-style diet lived a little longer.
September 5, 2013

3.   The contribution of diet and lifestyle to socioeconomic inequalities in cardiovascular morbidity and mortality.
   It has long been known that people of more privileged socioeconomic background live longer on average. For example, the more years of school you have had and the more stable your employment, the longer you live. This study investigated why. They found that most (70%) of the benefit of education on preventing heart disease is because people with more education tend to have better diets and exercise habits. So education causes better eating and exercise which causes less heart disease which causes less death. That's most of the story anyway.
September 5, 2013

1.   The “New Deadly Quartet” for Cardiovascular Disease in the 21st Century: Obesity, Metabolic Syndrome, Inflammation and Climate Change: How Does Statin Therapy Fit into this Equation?
   The authors cite evidence that particulates in the atmosphere are driving a significant amount of cardiovascular disease.
December 16, 2013

2.   Recent progress on nutraceutical research in prostate cancer
   Those who drank soymilk daily had 70% lower rate of prostate cancer than abstainers. men with prostate cancer who ate more fruits and veggies reduced their risk of progression by 59% relative to those who are the least. Green tea reduced the rate of widespread prostate cancer. In short, eating a plant-based diet and avoiding the usual suspects (meat, dairy, and eggs) is our best medicine against prostate cancer. Far tastier than PSA tests and digital rectal exams (yuck).
December 27, 2013

1.   Choice of motorcycle helmet makes a difference: a prospective observational study.
   In emergency room circles, they call them donorcycles, because that's where organ donations come from. For every mile ridden on a motorcycle, the rider has 35 times the risk of dying relative to riding in a car. But if you in that demographic of safety-conscious motorcycle riders, hear this: Riders who wear Full Face Helmets enjoy about 1/5 the risk of having a facial fracture.
September 5, 2013

2.   A prospective study of carpal tunnel syndrome: workplace and individual risk factors.
   Carpal tunnel syndrome (CTS) occurs most commonly with forceful hand exertion. Obesity triples your risk of CTS.
September 11, 2013

3.   Randomised clinical trial: sodium alginate oral suspension is non-inferior to omeprazole in the treatment of patients with non-erosive gastroesophageal disease.
   Sodium alginate oral suspension was as affective as omeprazole (Prilosec), for regular-old espohageal reflux (GERD), without ulcers or other erosions. Omeprazole and other proton-pump inhibitors (PPIs) are know to increase risk of some infections and of bone thinning. 
September 14, 2013

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